Hydrogen Sulfide and Cellular Redox Homeostasis
نویسندگان
چکیده
منابع مشابه
Hydrogen Sulfide and Cellular Redox Homeostasis
Intracellular redox imbalance is mainly caused by overproduction of reactive oxygen species (ROS) or weakness of the natural antioxidant defense system. It is involved in the pathophysiology of a wide array of human diseases. Hydrogen sulfide (H2S) is now recognized as the third "gasotransmitters" and proved to exert a wide range of physiological and cytoprotective functions in the biological s...
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The recognition of hydrogen sulfide (H(2)S) as an endogenously produced gas with signaling potential has stimulated research on a multitude of physiological effects mediated in the cardiovascular, immune, gastrointestinal, genitourinary, endocrine, and central nervous systems. The heightened activity in the area of H(2)S biology led to convening of the first international conference on H(2)S in...
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متن کاملThe Redox Biochemistry of Hydrogen Sulfide
H2S, the most recently discovered gasotransmitter, might in fact be the evolutionary matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase in mice leads to cardiovascular dysfunction and marked hypertension, suggesting a key role for this enzyme in H2S production in the vasculature. However, patients with inherited deficiency in γcystathionase apparently...
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ژورنال
عنوان ژورنال: Oxidative Medicine and Cellular Longevity
سال: 2016
ISSN: 1942-0900,1942-0994
DOI: 10.1155/2016/6043038